TOP Doctors for Liver Cancer Treatment

Oncologic diseases are accepted by many people as a death sentence. But it is far from truth. Today’s medicine in Germany offers progressive and efficient treatment methods, high-tech medical equipment, excellent professionalism of specialists who can successfully manage pathologies that yesterday were considered as incurable. Liver cancer treatment is not an exception. Liver cancer is the 5th most popular malignant disease in the world. More than 250 000 people are diagnosed liver cancer every year. This disease is met twice more often in men.

Oncologic diseases are accepted by many people as a death sentence. But it is far from truth. Today’s medicine in Germany offers progressive and efficient treatment methods, high-tech medical equipment, excellent professionalism of specialists who can successfully manage pathologies that yesterday were considered as incurable. Liver cancer treatment is not an exception. Liver cancer is the 5th most popular malignant disease in the world. More than 250 000 people are diagnosed liver cancer every year. This disease is met twice more often in men.

The following aspects influence the pathologic development:

  • liver cirrhosis;
  • Non-efficient treatment of hepatitis B and C;
  • Hemochromatosis;
  • Female birth control medications;
  • Anabolics, steroids;
  • Smoking;
  • Chronic alcoholism;

Primary liver cancer is not very common but, in latest years, growing disease. Hepatic cancer is a cancer which develops in liver itself but not migrate from the others cancerous lesions. Normally, it is associated with other chronicle liver diseases, especially, with cirrhosis. It is life threatening condition that needs immediate measures to reduce the risks it further development.

What Are the Liver Cancer Symptoms?

Early you could hardly notice symptoms of developing hepatic cancer as it, similar to many others malignant diseases, starts developing asymptomatically. The first signs you are able to notice are:

  • Pain in the right upper part of abdominal area
  • Loss of appetite
  • Sickness and vomiting
  • Enlarged liver that is possible to feel

With time some other symptoms appear as:

  • Yellowish skin and the whites of the eyes
  • Feeling full after small portion if meal
  • Weight loss without any other reason
  • Itching skin
  • Fatigue and weakness

Sometimes liver tumor can result in quite specific symptoms in men as

  • Gynecomastia (enlarged breast in men)
  • Testicular shrinkage

Those symptoms are explained by hormonal changes caused by liver tumor.

Women can notice such sings of possible hepatic cancer as white or pale fingernails.

Advanced Liver Cancer

In Stage 4 (advanced) liver cancer metastases are spread from initial source throughout the body to distant parts or/and invade lymph nodes. The symptoms of advanced cancer depend on which organ is affected.

Abdomen. You may have fluid in abdominal area which makes you feeling swollen and uncomfortable.

Obstruction. If cancer occupied the bowel it can lead to obstruction when tumor blocks intestinal lumen.

Lymphatic metastases. Lymph nodes become swollen and pain.

Kidney problems. Secondary tumor in kidney can cause ureters blockage and stop urine flowing.

Bones. If metastases spread to the bones it leads to the bone pain and makes the bones fragile and easy fractured.

Brain. When cancer spread to the brain it results in multiply symptoms including headache, inability moving, seizures, and difficulties seeing, hearing and speaking.

Lungs. Breath shortage is one of the main symptoms of metastases in the lungs.

Secondary Liver Cancer Symptoms

Secondary liver cancer unlike primary one is a result of migration of cancerous cells from another location which is primary source of malignant disease. It does not have any special symptoms but common as:

  • General weakness of the body
  • Night sweat and fever
  • Sickness and weight loss and others

Final Stage Symptoms

In final stage of liver cancer the following symptoms develop:

  • Jaundice (yellow tincture of skin and eyes)
  • Poor blood clotting (as liver could not support it anymore)
  • Fluid in abdomen
  • Brain dysfunction (partial or complete)

The Modern Diagnostic Methods for Hepatic Cancer

There are a number different diagnostic techniques and what to choose depends on many factors as disease degree, general health condition of a patient, cancer location and others. A doctor starts from evaluating physical examination of the patient and necessary Lab tests.

A few blood tests could be done as general, biochemical, and a test for presence AFP agent which is a good indicator of presence of hepatic cancer.

When laboratorial test allow determining cancer by changing chemistry, the other means as ultrasound, MRI, CT scan, and angiography help to find a tumor location and estimate its size. For the same purposes in Germany laparoscopy is also used, which is examination of inner space with telescopic tube. The advantage of the method is that it could combine diagnostics and surgical treatment in one session. With that minimally invasive technique it is possible to perform sparing liver resection.

Biopsy is a most reliable method to reveal abnormal cells in tissues sampling.

The method of diagnostic and treatment is always chosen individually. If you do not know what is preferable in your case you can ask professionals.

Experts in Cancer Diagnostics and Treatment in Germany

It is not possible to cope with liver cancer alone and for successful treatment you need professional help in specialized cancer center. German clinics offer comprehensive approach and help of expert in the different fields of cancer treatment. Depending of disease degree and patient’s priority it is possible to have consultation with an oncologist, cancer surgeon, radiologist, specialist in chemotherapy and others physicians in related fields. Using the services of GMG you can ask expert a question on any of your problem. Stay in touch with best doctors of your choice with support of GMG.

Diagnostic procedures are aimed at getting maximum information about the patient’s condition, the tumor peculiarities, metastases existence and location, and other factors that help to choose maximally efficient therapy. These procedures include:

  • Laboratory tests;
  • Alfa-fetoprotein;
  • specific markers;
  • Biopsy;
  • Angiography for analyzing vessels that feed cancer cells;
  • Laparoscopy: a specialist can study the tumor features via a camera and get material for cytological test;
  • Ultrasonic scan;
  • Contrast 3D layer-by-layer tomography:
    • Magnetic resonance;
    • Computer;
  • PET-CT

Day by day medicine in Germany evolves, and innovational, maximally efficient and sparing treatment methods are implemented. The treatment includes a few methods:

Surgical treatment

Operative intervention is the most effective way to fight the liver cancer tumor. Lobectomy is a resection of an unperceivable part of liver together with the tumor.Hemihepatectomy is an amputation of the major liver part. There is left and right hemihepatectomy.

Liver transplantation treatment

The transplantation of a donated organ is the only efficient way to fight a severe form of liver cancer. Getting donated material is possible in two ways:

  • Liver of the dead donor
  • Liver of the living donor

In some period of time after the transplantation the liver gains 80-85% of its nominal weight. By the moment the liver becomes fully functional, its work is supported by artificial liver apparatus.

Chemotherapy threatment

Health aids that destroy cancer cells are injected or taken in pills. Besides, chemotherapeutic agents are injected right into the liver with the aim of a catheter.

Radiotherapy and radiosurgery treatment

Radiation exposure is used for destroying the tumor or reducing its size before the surgery or after it for final inhibition of cancerous cells.
Cyber-Knife, the newest method of extra-precise exposure is used for removing metastases.

SIRT

This procedure implies selective inner beaming. Tiny radioactive balls are inserted into the malignant tumor via catheter. Then Yttrium-90 active agent radiumizes the tumor from the inside during a few days destroying it.

Proton therapy

Maximally precise effect on cancerous cells without damaging healthy tissues is provided by proton therapy. Protons pass through the healthy cells on a high speed and gives out energy only at the breaking moment in the tumor.

Ethanol injection

This method requires the injection of 96% ethanol under ultrasonic control with the help of a special needle. If the result is positive, the procedure can be repeated. Big tumors (above 5 cm in size) require bigger doses. Ethanol treatment is conducted under narcosis.

Thermal (radiofrequency) ablation

In thermal ablation the needle is inserted into the tumor and a laser beam is emitted. It burns out the tumor without injuring healthy tissues. The radiofrequency ablation implies the same procedure with an electrical generator instead of laser.

Cryotherapy

Cryo treatment of liver cancer is performed by affecting the tumor by low temperatures. Liquid nitrogen is injected via cryoprobe into the tumor, destroying the cancer cells.

Transcatheter embolization

This method is used for the therapy of unresectable tumors. Lipodiol with cytostatic is injected into the tumor. Then the tumor arteries are embolized that leads to the inhibition of tumor.

The treatment in the leading German clinics is performed with using the newest technologies and high-tech equipment. Our specialists will help you to fight this serious disease!

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Hepatocellular carcinoma (liver cancer) is fast growing, has poor survival rates, and has inefficient current treatments. Can they be improved? 2019-05-03 Liver Cancer Treatment
Profiles of Doctors for Liver Cancer Treatment

Latest News in Liver Cancer Treatment

Innovative treatment of liver cancer at the Klinikum Landshut

02.05.2019

Liver cancer remains unrecognized in many patients for a long time, often the tumor is only discovered at an advanced stage. For a larger infestation there is a new treatment method at Klinikum Landshut: millions of radioactive micro-beads flow directly into the liver. The first patients have already been successfully treated.

In the first four patients, the procedure went smoothly. This was reported by Prof. MD Matthias Dollinger, Chief Physician of the Medical Clinic I and liver specialist at the Klinikum Landshut on Tuesday to the media. The four patients were treated with selective internal radiotherapy, SIRT for short. "SIRT is intended for patients in whom the liver tumor can not be surgically removed," explains Prof. Dollinger. These can be either primary liver cancer or metastases. "This is a medical quantum leap for Landshut," says Managing Director MD Philipp Ostwald. Selective internal radiotherapy is only available at hepatology centers at university hospitals.

The goal of the therapy: to reduce the liver tumor as much as possible. "We want to increase the quality of life of our patients and extend their life expectancy," says Prof. Dollinger. The procedure gives similarly good results as a chemotherapy, but does without their side effects and is thus more gentle, so Dollinger. "Ideally, chemotherapy is unnecessary or we can delay it."

The process involves introducing millions of radioactive beads directly into the liver tumor. The procedure takes about 90 minutes under local anesthesia - six experts of the hospital care for the patient, i.a. a radiologist, a nuclear medicine specialist and a gastroenterologist. Through a small puncture, a catheter is passed through the artery to the liver - through this small, flexible tube the radioactive beads flow into the tumor. The microspheres are small enough to pass through the hepatic arteries but too large for the blood vessels in the tumor where they stick. The substances develop their effect exclusively in the liver, where they selectively irradiate the malignant cells and finally reduce them. Several clinical studies have shown that selective internal radiotherapy can greatly reduce liver tumors. Some tumors shrink to the point where they can eventually be surgically removed.

Patients need not be afraid of radiation. The radioactive microspheres have a very short range of a few millimeters. "The healthy tissue is loaded as little as possible," explains MD Bernhard Scher, chief physician of nuclear medicine at the hospital. Normally, patients will be discharged home one to two days after the procedure. The treatment team monitors progress. Required for the new range of therapies SIRT was also a state-of-the-art angiography facility.

About one to two weeks before the actual treatment begins, the patient must go through some preliminary examinations. A so-called mapping prepares the liver for the radioactive microspheres. Using angiography, a radiologist obliterates the vessels in the organ, so that the microspheres only do their work in diseased tissue and do not get outside the liver. "In this test phase, the patient is also given the first globules," says Prof. Dollinger. Only then is it clear whether the patient can be treated with SIRT. In addition, the liver should be exclusively or mainly ill. At the same time, the organ must be reasonably healthy and work satisfactorily.

Cirrhosis End Stage: Cell Therapy Makes Hope

01.05.2019

Alcohol, fat food, stress, medication: at some point too much for the organ. Good chances of recovery for the cirrhosis end stage now promises a cell therapy. Read more about the procedure here.

Cirrhosis is the late stage of chronic liver disease. The prognosis in end-stage cirrhosis of the liver has been very poor so far. Hope tests to patients in the Hospital Lindau and in the hospital Homburg / Saar give reason for hope. There, in two-thirds of patients, liver values ​​stabilized due to the novel treatment developed in Germany. In the process, healthy cells are recovered from the diseased liver. These liver cells are then treated in the laboratory, applied to special carrier material and then reinserted into the body in a second OP.

The new cells take on the carrier liver functions such as the detoxification of the body and the production of protein albumin (it transports fatty acids, vitamins and blood clotting factors).

In more than 50 patients with end-stage cirrhosis of the liver, the procedure (term: HeparAutoCell therapy) has been used so far. And for 20 patients, long-term experience of more than two years is available. The patients feel well after the therapy and in many cases after a few weeks, they are also able to perform well again.

Typical symptoms such as water in the stomach, tiredness and blood clotting disorders improved significantly. The clinical results show that the method improves liver function in patients with end-stage cirrhosis and prolongs their life expectancy.

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