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Bariatric Surgery

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After ten years of the German register "Bariatric Surgery" the data of more than 45 000 patients are available. The choice of the procedure is always a case by case decision, there is no gold standard. Although Germany occupies a leading position in the incidence of obesity and type 2 diabetes, the number of bariatric interventions in relation to the population is significantly lower than in neighboring countries. The frequency of operations in the presence of morbid obesity is currently 10.5 per 100 000 adults. It is many times higher in other European countries (Sweden: 114.8, France: 86.0, Switzerland: 51.9).

There is no gold standard for bariatric interventions. A process choice based on objective parameters is therefore unthinkable. The choice of surgical procedure is always a case-by-case decision. The German Bariatric Surgery Registry (GBSR) allows a retrospective analysis of the situation in bariatric surgery since 2005. This prospective observational study, also known as the "Quality Assurance Study on the Adiposity Operative Surgery", provides comprehensive information on diagnostics, surgical therapy, postoperative course and long-term outcome metabolic-surgical interventions of 45 121 patients.

The average age of the patients was 42.7 years, with 71.5% (n = 28 395) significantly more women than men (28.5%, n = 11 316) underwent such surgery. The obesity-associated comorbidities increased steadily during the observation period, with 90.26% of men and 85.05% of women having at least one comorbidity at the time of surgery. At 50.67 kg / m2 men had a significantly higher BMI than women at 48.69 kg / m2.

The number of obese people is increasing dramatically worldwide. One can even say that the disease is spreading like an epidemic or even pandemic. According to the current WHO data, approximately 21.3% of German citizens are obese, i.e. they have a BMI of more than 30 kg/m².

BMI of 35 kg/m² is considered the Obesity Grade II, BMI of more than 40 kg/m² is the Obesity Grade III. The health implications are dramatic: obesity causes numerous secondary diseases, most importantly diabetes mellitus and cardiovascular diseases. Besides different types of cancer are more common in obese people than in people with normal weight.

In addition, higher health costs and sick leaves greatly impacts the person economically.

Because of morbid obesity individuals usually experience a significant reduction of quality of life, they also are often confronted with social exclusion and prejudice. Surely every obese person has heard the well-intentioned advice: "Eat less and move more", even though this advice certainly is a good way to prevent obesity, it does not provide an effective therapy. Overweight patients who in addition to exertional dyspnea also have severe joint pain or degeneration, will only be able to follow this recommendation partially.

At the same time, modern people are moving less, hard physical work has become much rarer, cheap high energy food is everywhere and is aggressively advertised. All these factors have contributed to the sudden increase in obesity, seen since the 1970s in almost all industrial and newly industrializing countries.

Since conservative therapy has a rather low efficacy and therefore cannot solve the problem for the majority of patients, surgical procedures have been developed that can alter the anatomy and physiology of food intake to make the rapid and sustainable weight loss possible.

The United States of America is obviously ahead of Germany in the development of obesity. The number of surgical interventions to treat morbid obesity have increased in such a way that they have already overtaken the two most frequent interventions: gallbladder removal and hernia operation. These interventions are being carried out more and more often in Europe, too.

An operative reduction of pathological excess weight always represents a considerable intervention in the body anatomy and physiology and sometimes has a critical influence on food digestion and metabolism. In addition, there are always risks associated with a major surgical procedure. Therefore, a surgical treatment should never be the first option, it can be chosen only if all other therapy methods have failed or promise no success.

At present, the operations are not reimbursed by health insurance companies by default, each intervention must be applied for and motivated individually. A health insurance company will take over the costs of such an op taking into account not only medical criteria of its usefulness: one should also comply with further conditions. The following criteria should be met:

  • Patients should be between 18 and 65 years old.
  • Their BMI should be greater than 40 kg/m² or if the BMI is over 35 and patients suffer from health problems that are associated with severe excess weight, e.g. diabetes, joint diseases, heart problems or snoring with regular suspending of respiration (sleep apnea).
  • The patient has been overweight for more than 5 years.
  • A multimodal conservative therapy has been conducted for more than 6 months and had no effect.
  • Patients have no other diseases that could cause the overweight.
  • Sufficient compliance.
  • No excessive consumption of alcohol or drug abuse.

A conservative therapy attempt is considered sufficient if the treatment concept has elements from the three key pillars: movement, nutrition and behavior. The therapeutic approaches from these sub-areas must be coordinated and carried out simultaneously. Medications can be used to support them.

Restrictive and malabsorptive procedures: Commonly used restrictive procedures include gastric banding (GB) and sleevegastrectomy (SG) or tubular stomach. While the gastric band ties up the diameter in the upper part of the stomach, the tube stomach is formed by a left-lateral gastric resection. This not only reduces the size of the stomach, but also eliminates hormone-producing components that affect satiety.

The Roux-Y Gastric Bypass (LRYGB) is a more complex intervention, not only restrictive, but also malabsorptive. There remains a small gastric pouch, which is directly connected to the jejunum, the passage through the duodenum and large portions of the jejunum is switched off. Other malabsorptive procedures, such as bileopancreatic diversion (BPD), in which only about 100 cm of passage remain in the small intestine, as well as BPD with duodenal switch (DS), play hardly any quantitative role in Germany.

Choice of procedure: After the gastric bypass (RYGB) with 17 215 operations, the Sleevegastrektomie (SG) with 15 795 documented procedures is the second most common procedure. It also shows the highest percentage increase over the entire period. Complex malabsorptive processes are currently playing a minor role in Germany. The implantation of a gastric band (GB) has been carried out since 2005 in 4 124 cases and is therefore in third place.

There was a significant decrease in gastric band implantation throughout the study. Patients with GB were significantly younger at 40.5 years than patients with all other procedures. In addition, they had a significantly lower BMI of 44.92 kg / m2.

Patients who underwent SG had a significantly higher BMI and a higher incidence of comorbidities compared to all other procedures. In particular, the frequency of cardiac comorbidities, diabetes and sleep apnea.

The RYGB gastric bypass has been performed since 2005 in 17 215 patients. There was a clear preference for laparoscopic access, which accounted for 98.6% of interventions. Patients with RYGB (47.92 kg / m2) had a significantly lower BMI than patients with other procedures (50.27 kg / m2).

The more complex BPD (n = 148) was performed in 17 institutions participating in the study. The patients are older (43.4 vs. 42.7 years) and have a higher BMI (52.79 vs. 49.24 kg / m2) than patients with other procedures. The DS was conducted in 16 participating institutions as a one-time operation in 168 cases. Patients with duodenal switch are on average the oldest patients (46.7 versus 42.7 years) compared with other surgical procedures.

Between 2005 and 2014, 3 371 re and 2 039 re-do operations were undertaken. The percentage distribution of revision procedures on the surgical procedures was shown in the table. Most frequent were revisions to primary GB (44.7%) for late complications such as slipping, ligament defects, or esophageal motility disorders.

The aim of these procedure is to reduce the amount of food that can be eaten at once. This way the patient starts feeling full faster and the sensation stays for a longer time. The classic example of such operation method is the Swedish adjustable gastric banding (SAGB).

Gastric banding

A minimally invasive operation (laparoscopy) is used to place an adjustable gastric banding around the upper part of the stomach. It can be filled from the outside through a port chamber with liquid thus narrowing it. Larger food portions can cause vomiting or esophagus stretching. If this happens too often, the banding becomes ineffective.

The gastric banding is a foreign body, but it is usually well tolerated. In principle, the banding can remain in the body for a lifetime – even when the desired weight has been reached. If it gets removed, the patient usually regains weight.

Restrictive procedures, such as the gastric banding, demand the collaboration and cooperation of the patient in order for the therapy to be successful.

Sleeve gastrectomy

In case of sleeve gastrectomy or left lateral stomach resection a large part of the stomach is surgically removed from the body. Thus, a gastric tube is formed which can hold much smaller amount of food than before.

Its function is primarily restrictive, similar to the gastric banding. However, an additional effect of the "sleeve" is that the part of the stomach is resected, which produces certain hormones responsible for the sensations of hunger and satiety. This includes, for example, the ghrelin.

Thus, the sleeve gastrectomy not only limits the amount of food the stomach can hold, it also changes the hunger, saturation and taste sensations, resulting in a reliable weight loss.

Obesity is often associated with a number of metabolic disorders that form the so-called metabolic syndrome. These include severe metabolic disorders such as insulin resistance, dyslipidemia, type 2 diabetes mellitus and others. These diseases are also considered to be cardiovascular risk factors: they seem to favor the development of arteriosclerotic cardiovascular diseases directly. Myocardial infarction and cerebral infarction are the most unfavorable endpoints. In addition, dyslipidemia results in steatohepatitis (non-alcoholic fatty liver), a chronic liver disease that can dramatically convert to cirrhosis.

Metabolic surgery provides patients with excellent opportunities in achieving complete cure of type 2 diabetes mellitus, dyslipidemia and insulin resistance. The state of steatohepatitis can also be improved and cirrhosis averted.

Regarding diabetes mellitus type 2, insulin therapy after surgery is often superfluous, regardless of the amount of previously needed insulin. For example, a reduction of 300 IU insulin to zero is possible. The improvement in dyslipidemia usually occurs within a year after surgery, in parallel with weight loss.

Regarding the type of treatment, we offer a customized therapy with many options, from sleeve gastrectomy (gastric tube formation) to gastric bypass to biliopancreatic diversion with or without duodenal switch.

These procedures are aimed to alter the digestive physiology in such a way that only part of the consumed food is absorbed by the body. This naturally reduces the amount of calories ingested. However, this procedure also has disadvantages: in the same way severe vitamin deficiency symptoms can occur as well as steatorrhea and extreme flatulence. The classical representative of such surgeries is the biliopancreatic diversion (BPD), which belongs to exceptional indications.

Gastric bypass

Gastric bypass is a classic example of the combined type of procedures. A small part of the stomach, a so-called pouch is surgically separated from the rest of the stomach, still remaining in the body. A part of the small intestine is anastomosed to the upper stomach, so that the duodenum and the proximal part of the jejunum are excluded from of the food passage and the alimentary limb is separated from the biliopancreatic limb.

Only much later in the Roux-en-Y jejunum anastomosis the digestive enzymes meet the food bolus. Only from here the digestion takes place as usual. Since the alimentary limb, i.e. the part through which the food gets transported without digestive enzymes, is approximately 150 cm long, the surgery was considered to cause a certain malabsorption. However, this fact is now disputed, at least with this length of the digestive limb.

After a gastric bypass operation, the patients first feels no or much less hunger, the sense of taste and smell changes and they lose weight very rapidly. However, this cannot be explained by restriction or malabsorption alone. Surprisingly, the total energy consumption of the body increases after the operation despite significantly reduced calorie intake. In contrast, a diet with reduced energy consumption automatically lowers the basal metabolic rate, which makes further weight loss more difficult and when the diet is over leads to a rapid weight regain.

Diabetes mellitus is also dramatically affected. Probably due to the exclusion of duodenum and the early contact of food with the distal jejunum, there is a series of humoral changes that can break the extreme insulin resistance. Many patients who required high doses of insulin before the surgery are able to significantly reduce or even eliminate its intake altogether.

This effect is so great that it is now debated whether to operate patients with normal weight or only slightly obese diabetics if the diabetes can no longer be controlled in a conventional way. This metabolic surgery will probably prevail even more in the future, even if the mechanisms behind the effects are not fully understood at the moment.

Nowadays all bariatric surgeries can be carried out minimally invasive with tolerable risk, but they should be performed in an interdisciplinary centre in which all the disciplines involved in conservative therapy, diagnostics, preparation and implementation of the operation and, above all, the life-long aftercare of the patients work together. In order to prevent deficiency symptoms, patients must also take vitamins and micronutrients for their whole life after the gastric bypass operation, as they are absorbed in the proximal gastrointestinal tract. Diagnostics and treatment of other complications requires a lot of experience and expertise.

In 2009 the German Society for General and Surgery therefore drafted special guidelines, that allow clinics to get certified as obesity centres. In addition to certain infrastructural requirements, an obesity-experienced surgeon team and a minimum number of performed bariatric interventions are required.

Although these operations are very popular and the results in many cases is stunning, yet the gastric bypass and other obesity surgeries are not miracle remedies. If the doctors believe you are a good candidate for the procedure, they will surely explain to you that the operation alone does not guarantee that you will be able overcome obesity or maintain a healthy weight for a long time. In order to achieve tangible and lasting effects, it is necessary to maintain a strict dietary plan and do exercises. A scalpel can do nothing to improve your commitment and willpower.

GermanMedicalGroup + 49 (7221) 39-65-785 Flugstrasse 8a 76532 Baden-Baden Germany According to the current WHO data, approximately 21.3% of German citizens are obese, i.e. they have a BMI of more than 30 kg/m². According to the current WHO data, approximately 21.3% of German citizens are obese, i.e. they have a BMI of more than 30 kg/m². 2018-07-31 According to the current WHO data, approximately 21.3% of German citizens are obese, i.e. they have a BMI of more than 30 kg/m².

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