Azoospermia means that at least two sperm samples in the ejaculate contain no sperm. About 1% of all men are affected by azoospermia; it is 10-15% among men with reduced infertility and infertility problems. Infertility means the reduced ability to reproduce.
Azoospermia can be due to an error in the production of sex hormones, a disease of the testicles or the vas deferens, or problems with intercourse and ejaculation.
A reduced excretion of stimulating hormones from hormonal glands in the area of the brain (gonadotropins from the hypothalamus and pituitary) leads to the fact that the production of sex hormones remains low (hypogonadotropic hypogonadism). Because of the lack of sex hormones, the development of sperm does not occur in men. Drug treatment with a gonadotropin preparation usually improves the sperm quantity and quality of these men.
Damage to the testicles can lead to very little or no sperm production, even though there are sufficient sex hormones available to the body. The sperm production then remains too low for sperm cells to get into the sperm.
A common reason for azoospermia is testicular retention, in which the testes after the embryonic stage have not completely descended from the abdominal cavity into the scrotum (undescended testicles). Testicular retention is present in 3–5% of all male newborns. It can be identified as the cause of azoospermia in about 20% of all men in whom no sperm cells are detected in the sperm. Since the testicles are located further up in the abdomen or in the inguinal canal, the extraordinarily temperature-sensitive germ cells located in them are surrounded by higher temperatures and die. About 50% of men with unilateral testicular retention and 75% of men with double-sided testicular retention are sterile.
Another cause of testicular damage is the appearance of mumps disease after puberty. Around 25% of men who develop mumps develop an inflammation of the testicles (orchitis) at the same time, which can damage the germ cells to such an extent that azoospermia develops as a result.
8–14% of men with azoospermia have different chromosomal abnormalities, while less than 1% of the population have such abnormalities in relation to the total population. The most common variant is Klinefelter syndrome.
Surgery on the testicles, radiation therapy or chemotherapy can also lead to the development of azoospermia. It is important, therefore, that men who are scheduled to receive such treatment receive information about how to remove and freeze sperm before starting treatment. This makes it possible to have fertility treatment at a later date.
Azoospermia can also indicate testicular cancer. If testicular cancer is present, sperm cells can only be detected in tissue samples from the testicle in question, it should be checked whether they can be used in a subsequent treatment of a possible male infertility.
Why azoospermia occurs? This question is asked by many men. This issue is of concern to all men who face such a diagnosis. The exact cause can in many cases not be identified. Among the most frequent causes there are:
The prognosis of azoospermia depends on the etiology. The pretesticular and post-testicular abnormalities as azoospermia reasons are in most cases well treatable. Fertility clinics in Germany, Switzerland or Austria will facilitate the restoration of fertility potential and solve the health problem as soon as possible.
The andrology centers in Germany offer the whole scope of modern methods for male infertility treatment. The cost and type of male infertility treatment in Germany depends on the type of azoospermia, its etiology, age of the patient and other important issues. Before doctors of our infertility center start the azoospermia treatment, they carry out a lot of procedures and trials for correct diagnosis identification:
Further assessments in the clinic are not provided, however if a patient wants to get a full image of a disease and if the azoospermia treatment is not possible, this patient is sent to a proper specialist.
Azoospermia treatment at reproductive health centers in Germany, Austria and Switzerland directly depends on its type and, therefore, the causes that led to this disease. A mild case of a disease can be cured by using a pharmaceutical azoospermia treatment: hormonal therapy and antibiotic medication in order to get rid of an inflammatory process. In the case of vas deferens injury, a surgery for patency recovery is carried out if reasonably. The surgical way can eliminate other disease causes.
Obstructed azoospermia (OA) is characterized with absence of spermatozoa in the ejaculate despite of physically normal spermatogenesis. In case of obstructive azoospermia, treatment requires biopsy. As a result of the biopsy procedure, spermatozoids can be extracted from the testes for IVF, ICSI, IMSI and PICSI methods. Biopsy that was mentioned above is carried out with a help of the following methods:
The progress of German reproductive medicine gives much hope to patients with azoospermia. One of the most efficient ways to treat azoospermia is intracytoplasmic sperm injection (ICSI). The German andrologists advise this method even to patients with potentially treatable causes of infertility.
The sperm which has been obtained using a surgical microscope directly from the epididymis (epididymis) is brought to the special laboratory and prepared for further ICSI process. IVF treatment in Germany enjoys the highest success rates in Europe, which equals more than 45%.
There are some other methods of azoospermia treatment. The German clinicians exercise holistic and interdisciplinary approach. The main goal is to eliminate the pathological process which may cause azoospermia. Ayurvedic and homeopathic treatment of azoospermia have proved to be efficient complimentary methods for azoospermia and oligozoospermia treatment. Energy medicine, implemented at German fertility clinics, includes treatment of infertility with plant essences, acupuncture, relaxing and harmonizing techniques. A homeopathic treatment azoospermia can be carried out complementary to the conventional treatment. Homeopathy has significantly fewer side effects and can increase the chances of successful in vitro fertilization up to 55%.
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As seen, chances for an azoospermia treatment at the German infertility treatment centers are enough real. The clinic professionals will be glad to help international patients with all the available methods and will inform you in advance on cost for azoospermia treatment.